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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2841e087934fa0a14b4e0edb7e653608f7df8c4cbfa5edb7724d446372dc85f8' 
  AND token = 'xxxu/3w4hj23mimcF5q1h/Xa0ZBbYMh+IO/mp5E7xlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}