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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66dc9e462216c5e9d341fa85fbf4f18d7a814d5705d8b9fd69abad486a13aca3' 
  AND token = 'N9N1AukIkUNSuEbWVZTKjavKygVYaKV9HFMUOkIBftg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}