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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed3176c84822abe46e1c28680f1d36e8a084e1ae81c625fe6311ed00898bb7c' 
  AND token = 'DTZQV5PG7Y+oQWd2KMw1DMjyKyj2shNrFfSlYJEESi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}