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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d9e64dfdd0ee2771ea257594a95fa19bf429ec66a32374d86d049b50bfe2d9' 
  AND token = 'GMVIzm/wA13keJQ3mDZOB2z3AejvoyWdnpnQ2GFz6dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}