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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f08479b7f5a0e4bc33e05fb8671e03918405afb54301b707717ef9b174163e9d' 
  AND token = 'rE6Kbfg9f4Mx4My/8hZ1gyI2HpS3LtCo81lbu0Chexw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}