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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3d0cc5a952e19cabf5e94f2bc85ee0605d5f3704e138db0be9255a6a1f3318' 
  AND token = 'BEdqU8A//VHCq7+gn2jb7t91S0rTi18InHdjZvYQZ5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}