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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b0340b0f50b8532c0c1646107888ba9baf5f7ac0e5afe08e1710edd88cad3a' 
  AND token = 'tAoZplHY+iwZIZMeBpibz09/0KqKx60fQD+y0hhsPoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}