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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ef5c5c371af8827fba1011e3b1591089192c389dc6ef391dc9a1ec90c5db09' 
  AND token = 'fSHCDQA2B6m/cynWDBn7EvA/ggQxgY3zog5QUJv4A3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}