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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a4b1ffca0bc4b0a43fa36cec1be460bcc3386597ab5e78a8902d2f6552cc334' 
  AND token = '4V9Gryu0HbqzvukAYn6Tof8TgqkH6TBrcNImnYS8RDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}