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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b588f281355c76fa0668efa2512347e4d9099b96483c493a12737c1fa4e9301' 
  AND token = 'gM7ZC8PpZxaSlZ/vRV1j9vVrtc37P3RsQflCwRxcjQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}