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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b5bf4490101ac5efd7e4d9ee601749b8551012dead66d678746c58cc4175ba' 
  AND token = 'O63Cm43f3vgks4E5j264VfRdenTpd4YHQ0VjMElTEeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}