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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6cef29ac1f01d7f3b6d2ff70c3a8836b0d3e234407ec2533907d16adf1b4a8' 
  AND token = 'kaR0RoGBDVNsvacIgx3KhGhfX2EZANQLHtnbD1zDITE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}