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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b729e568c43bcf42a96ac39d0dec8f0700d24b16782765bde89dfa7527eb2166' 
  AND token = '7O0FAB5U5XmT+UckjkCtPla1BQ4hKsCotohf9eQiiyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}