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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '633d4baa807f9f729d028a15a760f85a14ea26be05961db51bce57a1650102b2' 
  AND token = 'yCVJ+DmSWEhCOkVXcl0wQTk2gUbvuIyK3d1RCkmdAn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}