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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1045bf5e375b4bcfa1d155d815458c4605a90d27dc5ad7712ed5d91a25238916' 
  AND token = '/gNtLy7+LWLicL1whWeaZe69oT5w0XEogb3gCycLlbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}