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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b05c9d9187fea09e771ad1c22e214004b8be3e6a4c043b5f913e6bd116dba13' 
  AND token = 'E2wBuFaTFKd6ztq0Tuu1Be2WCiPjJsKDfBo4VK6u03A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}