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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c5df4198dc7dc6ac577aa1966b962529131667477969d8f45a11ecbfb6d40f9' 
  AND token = 'Imr3sx0kgTIOv+oJ5lcLrfzGJ5QcOuFVn62depX6Lwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}