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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2f7cb658ddd10a9a650383688fcb53e7d9d8c7ede3e57bfa46e6b8227334be7' 
  AND token = '53/1Q1KUSf0JMAQ1C0uIAopkdf/EwLG0VCISXTKvMgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}