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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d5e1149a3b2737e18c073d36b488ab008c1b0a00d7cb9957508c5dca04fefe' 
  AND token = 'gotIv7OAFSTN33wmDLvJ2aVUvvGUe305spoaYXtX3jQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}