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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dae1d51d8bcf26414e366ce1023d5032e1966d2297b59d30578d5b54d23a704' 
  AND token = '4aFyHaAe1cuewRkdvgvVv4HD2zV3lLQpPHLbYYTCN8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}