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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52445fee527ec50b72b67661e5270c52b95d900c2d855f4978dc80207858f82f' 
  AND token = 'NRn5Ss8hZcdq3eqP7TOb3KShx3WUCYLChRfdRhiYA74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}