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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c427ab4525e4e9d0622914fd00535dbb00d04bbb14cff942a8e2ebe823fa23f' 
  AND token = '0nuKiYx2RoV8p491K0yLUe1gMg7mJoA4n4B55bWWfGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}