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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c08f11b79ef43c4ec9a2d65a3d9c1c2842c0f2689d09750b71151f7f89f9d7fe' 
  AND token = 'R7/7cSAw1VuaCDtJNastbzY+7DbLhZV6dU5a8SsMtb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}