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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ec30be8780244f751708a9826c978d177fadf27e9d974a28c44c42d243b4af' 
  AND token = '5OCbCdspqpx2+2UDxKCfK5e0Mc9uvFEQLrHpakyTqGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}