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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b55377aca7614fe8ad3b0e6ee3d1b581525e782802d2ba83db6393627b1fb7ad' 
  AND token = 'GpU8axKD/2kfcHAyESQWRGwwqvXPt33nE5+pEvJX7K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}