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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc9f259cf687e2d5c536c1faa1e8efb459a032c9a5b05a13f04bb6a034077442' 
  AND token = 'iGku6pXQXot5RRA4de+wVf1atnacOb0hTwALQ0E/XJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}