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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad72c94b5c2c7f6950953ac64af839427cfceeff04e5024cc2d066c62701720c' 
  AND token = 'lNzeUy3Smr2Z4+Mc+ve2NpSfoPCqHzU+Bxb0Ia4LtQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}