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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51cb8768ee3e8268f76c632cfc3cb4ddfc3456f5a5b81357087fe66d0d2e64e2' 
  AND token = 'MnlpfB7IbOXqqXT5Dwtbj9N5zXjEBSL4h7GhfU0rxQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}