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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '518e684a15a0da137b68d353375e08fba6bf09a5d8bbb24558c2e8b0a4003529' 
  AND token = '/DEmfu6GNuQQArKYVsqqvOzQ5gtjkWxQo8gk2qx2hDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}