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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af9296a8ffd55257a1c23933da691dcb85998882151208e8e31c3ffe4e24c1e1' 
  AND token = 'rVyoWQrrWSl5q3z3P8B1sfQTbggw90DXX4F4RB87N0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}