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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '754fe75ff954802cd17cabdd9e8061c84a5ec31958fcf8c86d3a4820556b82d5' 
  AND token = 'pONo9eIroPvvLfnu+qV3Ice9ypEoMF3obaWmSzdDu88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}