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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a422065cbd21c4e9c9113e894285303ec371ad8b80bac71970d165ddd643408' 
  AND token = '6rWIPgL/WL9yG2w6D41ucOdX1Lwdb+bUER7E3XW/cfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}