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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a4bcfa2d6bb4c319a0c12f3bf1b883be17e5180a86d2ad5099d49cf9090891' 
  AND token = 'Vd8NS7RItjoFptNiz0B0V7yUpFGTOCTF2bP1i3PG1jQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}