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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2888b78cbb1ddd45504c1bed735a20a5afd52367d0a5571fa57c312cd3220b7' 
  AND token = 'g6IQOn44bWtfrCYBb2PHuuFyUGOIFy5U2yFLmlWM7Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}