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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa1495868d31408187d3f14322921152bcd65cd2c3d1f826b9da8c930a69b1c8' 
  AND token = 'nFsRUX2x6q8l0+GprsmqD2THO1vu+HkweLNxYTkjZxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}