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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '355008ee63d8196d63f620900346de0e8cef68dc81933e5b371c0bbc5c77d68c' 
  AND token = 'gqwke09u0r6P/i1h6d5d+ODjRjYoKbwmC6+aeLRVYHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}