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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657168427a0eb00553456434455d14a51c7dd51287ca948739bf2188a97006f0' 
  AND token = 'sv/FZ2NG4wHom4HergnrTw7hyc+llvgwuyMb4u5asaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}