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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64633369749c9c0f66f8a128a6e669dec08822c2641a4244fe5a6cde521750da' 
  AND token = 'ei71VbV9LuhMb5dd+YJhUM3CWqDRUeYJDQ8LjRNbG/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}