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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a51a300d25a32f271efe919c359bcb661e8d3fcbf6b9b557623d5e29a2c6af0' 
  AND token = 'yxCaIFpirPna9yNtYrXmjl3c00Tqu5sXtzPiIGx3yD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}