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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19444844a65bfed250c9c4f30a4063927cbb1b37b5d989901efa2a58cb786517' 
  AND token = 'CTQ5/Y4iyXmAkOzn/j9UCN1CyHOqXruZFzJsSSFSdiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}