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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ce369b78fc334be8a9f7ce1dbf5911c7e639d19baba9590b9db89d03891819' 
  AND token = 'N+x6h91d1mWCpIy9A+DZUfmkn0pU6xj9TlkIfRLC7Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}