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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7231bbef19d4741be1f71db73465d2b297cecf5a2dcba623b6afdc5cb374a67' 
  AND token = '6FBHZ0TeJSWeBdrSICJD9Xqlp7QiGrdu0uXpJTsfVAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}