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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2527c9855e0ab2162e2614af943e8c123100bf79ccfa01d6493894b8d6d5a31' 
  AND token = 'IOrD47E113gCPCZ3Y+WZ6pdYMpmG21hzzjcCF2tPmg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}