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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cba9322202327b602fc9c7e5453d2eb648143a20e97ca8d32b5404bfb012560b' 
  AND token = 'CTDE3Nyz4aAVDntvkM3HRUNWSFX7nnjcBMhKCG53HW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}