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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eeaeaee2b45ac1b5c3664a3c0154fd9f380373f7e8cecb253f030821ef9b8f5' 
  AND token = '5STWACTKOgbFbKmGI+VR+icoqxdM1UZQA8YqyA8n64I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}