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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6647a47d2fa10cdb17c3273dd6926799e0be70f680937619d39cc27f0de22989' 
  AND token = '8srruKJVui/aG4WBJ12JJuyzjMCvY04lJxcBcQPtJxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}