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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a1af8781730c854cb9db509922faee8a4f8984e38a7e6d9b3105025724efb9d' 
  AND token = 'Y/kps+INVm2GaOelWbVTXqdZRWwNeWE0dt7pIM6Ezm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}