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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3a8b96e0a08a41768858fe6be92897fd882f98e1f80f682b2e091c76e56011' 
  AND token = 'MVgV6OX2MxxsTEw/xOAM+XJlYzbNlzB3+q1oSdsnigM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}