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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abd484e716eadda520e8f2e4aec28a25432177d505b84942241742ae0711f47e' 
  AND token = 'IPHHh6pRMvemUg6L++dmFEsUPR1QqlOhcOF7ZO7eILg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}