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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7db8615e730b6b9020cd7335d9b5b09342de3d9267d343de270540ac8d5f99b7' 
  AND token = 'r/WeiLvkGRutrLwRH3U7dB7CUWJLmK6quDdlGq3yWug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}